Figure 3
From: Influence of rutin and its combination with metformin on vascular functions in type 1 diabetes
Cumulative concentration-effect curves showing endothelial dependent relaxation responses to Acetylcholine (ACh) in endothelium-intact (+ ED), (a) abdominal aortic rings, (b) thoracic aortic rings. Rutin (100 mg/kg), metformin (300 mg/kg). Symbols represent means ± SD. # denotes p < 0.05 and ## denotes p < 0.01 versus response in vehicle-treated normal rat aortic rings; * denotes p < 0.05 and ** denotes p < 0.01 versus response in vehicle-treated diabetic rat aortic rings; $$ denotes p < 0.01 and $ denotes p < 0.05 versus response in rutin-treated diabetic rat aortic rings; ^ denotes p < 0.05 verses response in metformin-treated diabetic rat aortic rings.
