Figure 1
Finding the IC50 dose of Salinibacter ruber and Salinivenus iranica on breast cancer cell lines by MTT assay. (a) Effect of 10, 50, 100, 150 and 200 µg/mL of Salinibacter ruber metabolites in 24, 48, 72 h and after 48 h treatment and 48 h washout (WT) on 1. MDA-MB-231, 2. MDA-MB-468, and 3. MCF-7 cells. The viability of cells in 48 h and WT groups reduced to 50% after treatment with 100 µg/mL dose. (b) Effect of 10, 50, 100, 150 and 200 µg/mL of Salinivenus iranica metabolites in 24, 48, 72 h and after 48 h treatment and 48 h washout (WT) on 1. MDA-MB-231, 2. MDA-MB-468, and 3. MCF-7 cells. The viability of cells in 48 and WT groups was reduced to 50% after treatment with 100 µg/mL dose. n = 3.
