Table 17 Predicted moonlighting proteins.

From: Moonlighting genes harbor antisense ORFs that encode potential membrane proteins

Gene

Function

rpoC

DNA-directed RNA polymerase subunit beta'

gyrA

DNA gyrase subunit A

gyrB

DNA topoisomerase (ATP-hydrolyzing) subunit B

ligA

NAD-dependent DNA ligase LigA

typA

Translational GTPase TypA

ptsP

Phosphoenolpyruvate–protein phosphotransferase

infB

Translation initiation factor IF-2

purH

Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase

aspS

Aspartate–tRNA ligase

  1. These are genes that consistently occur in moonlighting-gene enrichment experiments, in all three model organisms (M. tuberculosis, E. coli, and S. pneumoniae). Their consistent co-enrichment suggests that they are, in fact, moonlighters.
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