Table 1 Baseline characteristics of AIS patients between good and poor prognosis.

From: Development and validation of a machine learning-based prognostic risk stratification model for acute ischemic stroke

Characteristics

 

Overall

Good

Poor

P-value

N

677

468

209

Age, n (%)

 < 60

383 (56.6)

265 (56.6)

118 (56.5)

0.965

 ≥ 60

294 (43.4)

203 (43.4)

91 (43.5)

Gender, n (%)

Female

279 (41.2)

183 (39.1)

96 (45.9)

0.113

Male

398 (58.8)

285 (60.9)

113 (54.1)

SBP, median [Q1, Q3]

 

143.0 [132.0,156.0]

139.0 [130.0,152.2]

149.0 [138.0,166.0]

 < 0.001

DBP, median [Q1, Q3]

 

87.0 [74.0,97.0]

84.0 [71.8,94.2]

90.0 [83.0,99.0]

 < 0.001

SD, n (%)

Anterior

270 (39.9)

174 (37.2)

96 (45.9)

0.054

Posterior

252 (37.2)

177 (37.8)

75 (35.9)

Anterior/Posterior

155 (22.9)

117 (25.0)

38 (18.2)

SOH, n (%)

Left

283 (41.8)

195 (41.7)

88 (42.1)

0.765

Right

270 (39.9)

184 (39.3)

86 (41.1)

Bilateral

124 (18.3)

89 (19.0)

35 (16.7)

SOS, n (%)

Cortex

155 (22.9)

111 (23.7)

44 (21.1)

0.308

Cortex-subcortex

155 (22.9)

107 (22.9)

48 (23.0)

Subcortex

186 (27.5)

121 (25.9)

65 (31.1)

Brainstem

104 (15.4)

79 (16.9)

25 (12.0)

Cerebellum

77 (11.4)

50 (10.7)

27 (12.9)

NOS, n (%)

Single lesion

470 (69.4)

319 (68.2)

151 (72.2)

0.329

Multiple lesions

207 (30.6)

149 (31.8)

58 (27.8)

Cholesterol, median [Q1, Q3]

 

5.3 [4.4,6.2]

5.2 [4.4,6.1]

5.7 [4.5,6.2]

0.005

Triglyceride, median [Q1, Q3]

 

2.2 [1.9,2.4]

2.2 [1.9,2.4]

2.2 [1.9,2.4]

0.28

LDL, median [Q1,Q3]

 

4.8 [4.3,4.9]

4.7 [4.4,4.9]

4.8 [4.3,4.9]

0.796

FBG, median [Q1, Q3]

 

5.3 [4.6,5.8]

5.2 [4.6,5.8]

5.3 [4.7,6.0]

0.142

HBALC, median [Q1, Q3]

 

5.6 [5.3,5.9]

5.6 [5.3,5.9]

5.7 [5.4,6.0]

0.055

HCY, median [Q1, Q3]

 

15.8 [12.7,19.4]

15.0 [12.2,18.5]

18.2 [13.9,20.8]

 < 0.001

UA, median [Q1, Q3]

 

349.8 [309.8,408.1]

346.9 [310.7,403.3]

357.8 [302.9,423.9]

0.261

MB, median [Q1, Q3]

 

97.7 [75.1,147.8]

96.8 [76.5,137.2]

98.6 [69.8,181.1]

0.106

CRP, median [Q1, Q3]

 

12.6 [7.7,17.6]

10.8 [7.2,15.3]

17.1 [9.6,21.4]

 < 0.001

FIB, median [Q1, Q3]

 

4.3 [4.0,4.8]

4.4 [4.0,4.8]

4.3 [3.8,4.7]

0.055

Ddimer, median [Q1, Q3]

 

174.0 [133.0,221.0]

175.0 [131.0,227.2]

170.0 [137.0,212.0]

0.284

BNP, median [Q1, Q3]

 

93.0 [73.0,162.0]

93.0 [74.0,163.0]

93.0 [71.0,157.0]

0.707

NSE, median [Q1, Q3]

 

16.2 [12.7,18.6]

14.5 [12.3,17.2]

18.7 [17.6,20.1]

 < 0.001

S100β, median [Q1, Q3]

 

275.0 [224.0,290.0]

268.0 [217.8,284.0]

292.0 [259.0,312.0]

 < 0.001

Thrombolysis, n (%)

No

473 (69.9)

346 (73.9)

127 (60.8)

0.001

Yes

204 (30.1)

122 (26.1)

82 (39.2)

Thrombectomy, n (%)

No

644 (95.1)

456 (97.4)

188 (90.0)

 < 0.001

Yes

33 (4.9)

12 (2.6)

21 (10.0)

Antiplatelet, n (%)

No

122 (18.0)

101 (21.6)

21 (10.0)

 < 0.001

Yes

555 (82.0)

367 (78.4)

188 (90.0)

Anticoagulation, n (%)

No

576 (85.1)

423 (90.4)

153 (73.2)

 < 0.001

Yes

101 (14.9)

45 (9.6)

56 (26.8)

Statin, n (%)

No

103 (15.2)

84 (17.9)

19 (9.1)

0.004

Yes

574 (84.8)

384 (82.1)

190 (90.9)

PPI, n (%)

No

535 (79.0)

401 (85.7)

134 (64.1)

 < 0.001

Yes

142 (21.0)

67 (14.3)

75 (35.9)

Dysphagia, n (%)

No

525 (77.5)

410 (87.6)

115 (55.0)

 < 0.001

Yes

152 (22.5)

58 (12.4)

94 (45.0)

SAP, n (%)

No

512 (75.6)

393 (84.0)

119 (56.9)

 < 0.001

Yes

165 (24.4)

75 (16.0)

90 (43.1)

  1. SBP systolic blood pressure, DBP diastolic blood pressure, SD stroke distribution, SOH side of hemisphere, SOS site of stroke lesions, NOS number of stroke lesions, LDL low-density lipoprotein, FBG fasting blood glucose, HCY homocysteine, UA uric acid, MB myoglobin, CRP C-reactive protein, FIB fibrinogen, BNP brain natriuretic peptide, NSE neuron-specific enolase, PPI proton pump inhibitor therapy, SAP stroke-associated pneumonia.
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