Table 2 Univariate and multivariate logistic regression analysis of risk factors for poor prognosis in AIS patients.

From: Development and validation of a machine learning-based prognostic risk stratification model for acute ischemic stroke

Characteristics

Univariate logistic analysis

Multivariate logistic analysis

OR

95%CI

P-Value

OR

95%CI

P-Value

Age

  < 60

 

Ref

Ref

   

  ≥ 60

1.01

(0.72–1.40)

0.967

   

Gender

 Female

 

Ref

Ref

   

 Male

0.76

(0.54–1.05)

0.097

   

SBP

1.03

(1.02–1.04)

 < 0.001

1.01

(0.99–1.03)

0.302

DBP

1.03

(1.02–1.05)

 < 0.001

1

(0.97–1.03)

0.979

SD

 Anterior

 

Ref

Ref

 

Ref

Ref

 Posterior

0.77

(0.53–1.11)

0.16

0.67

(0.4–1.11)

0.12

 Anterior/Posterior

0.59

(0.38–0.91)

0.018

0.64

(0.35–1.15)

0.138

SOH

 Left

 

Ref

Ref

   

 Right

1.04

(0.72–1.48)

0.849

   

 Bilateral

0.87

(0.54–1.38)

0.567

   

SOS

 Cortex

 

Ref

Ref

   

 Cortex-subcortex

1.13

(0.69–1.85)

0.622

   

 Subcortex

1.35

(0.85–2.16)

0.199

   

 Brainstem

0.8

(0.45–1.41)

0.444

   

 Cerebellum

1.36

(0.75–2.44)

0.304

   

NOS

 Single lesion

 

Ref

Ref

   

 Multiple lesions

0.82

(0.57–1.18)

0.288

   

 Cholesterol

1.21

(1.06–1.38)

0.004

1.12

(0.94–1.34)

0.203

 Triglyceride

1.27

(0.81–2.00)

0.297

   

 LDL

1.09

(0.87–1.37)

0.441

   

 FBG

1.14

(0.97–1.36)

0.121

   

 HBALC

1.51

(1.01–2.26)

0.045

1.25

(0.72–2.17)

0.421

 HCY

1.17

(1.12–1.22)

 < 0.001

1.24

(1.16–1.33)

 < 0.001

 UA

1

(1.00–1.00)

0.209

   

 MB

1

(1.00–1.01)

 < 0.001

1

(1–1)

0.421

 CRP

1.12

(1.09–1.15)

 < 0.001

1.05

(1.02–1.09)

0.004

 FIB

0.77

(0.59–1.00)

0.048

0.85

(0.59–1.23)

0.394

 Ddimer

1

(1.00–1.00)

0.45

   

 BNP

1

(1.00–1.00)

0.94

   

 NSE

1.45

(1.36–1.55)

 < 0.001

1.38

(1.27–1.51)

 < 0.001

 S100β

1.02

(1.01–1.02)

 < 0.001

1.01

(1–1.01)

0.005

Thrombolysis

 No

 

Ref

Ref

 

Ref

Ref

 Yes

1.83

(1.29–2.59)

0.001

0.78

(0.46–1.32)

0.358

Thrombectomy

 No

 

Ref

Ref

 

Ref

Ref

 Yes

4.21

(2.05–9.05)

 < 0.001

0.5

(0.16–1.55)

0.226

Antiplatelet

 No

 

Ref

Ref

 

Ref

Ref

 Yes

2.45

(1.51–4.15)

 < 0.001

1.04

(0.42–2.6)

0.932

Anticoagulation

 No

 

Ref

Ref

 

Ref

Ref

 Yes

3.43

(2.23–5.32)

 < 0.001

1.91

(1.03–3.56)

0.041

Statin

 No

 

Ref

Ref

 

Ref

Ref

 Yes

2.17

(1.31–3.79)

0.002

1.42

(0.55–3.66)

0.464

PPI

 No

 

Ref

Ref

 

Ref

Ref

 Yes

3.34

(2.28–4.92)

 < 0.001

1.47

(0.8–2.68)

0.21

Dysphagia

 No

 

Ref

Ref

 

Ref

Ref

 Yes

5.75

(3.92–8.52)

 < 0.001

3.77

(2.13–6.7)

 < 0.001

SAP

 No

 

Ref

Ref

 

Ref

Ref

 Yes

3.95

(2.74–5.73)

 < 0.001

1.54

(0.85–2.78)

0.157

  1. SBP systolic blood pressure, DBP diastolic blood pressure, SD stroke distribution, SOH side of hemisphere, SOS site of stroke lesions, NOS number of stroke lesions, LDL low-density lipoprotein, FBG fasting blood glucose, HCY homocysteine, UA uric acid, MB myoglobin, CRP C-reactive protein, FIB fibrinogen, BNP brain natriuretic peptide, NSE neuron-specific enolase, PPI proton pump inhibitor therapy, SAP stroke-associated pneumonia.
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