Table 1 Characteristics of the studies included in the meta-analysis.

From: Cardiorespiratory dose comparison among six radiotherapy regimens for patients with left-sided breast cancer

First author (year of publication)

Total patients (DIBH/FB)

Clinical stage

Median age (years)

Prescription dose (Gy)/fractions (F)

Plan types

Study type

NOS score

Angela 201721

64 (32/32)

NA

NA

50 Gy/25 F

3D-CRT

Retrospective

6

Bruzzaniti 201327

16 (8/8)

NA

51

50 Gy/25 F

3D-CRT

Retrospective

7

Chi. F. 201526

62 (31/31)

I or II

39.5

50 Gy/25 F

IMRT

Retrospective

8

Hepp 201525

40 (20/20 )

pTis–pT1 pN0

NA

50 Gy/25 f

3D-CRT

Retrospective

7

Jensen 201723

44 (22/22)

pT1-2N0M0

58

50 Gy/25 f

3D-CRT

Retrospective

7

Lastrucci 201722

46 (23/23)

NA

NA

50 Gy/25 f

3D-CRT

Retrospective

7

Corradini 201729 (3D-CRT group)

20 (10/10)

NA

NA

50 Gy/25 f

3D-CRT

Retrospective

7

Corradini 201729 (VMAT group)

20 (10/10)

NA

NA

50 Gy/25 f

VMAT

Retrospective

7

Pham 201624 (IMRT group)

30 (15/15)

NA

NA

50 Gy/25 f

IMRT

Retrospective

6

Pham 201624 (VMAT group)

30 (15/15)

NA

NA

50 Gy/25 f

VMAT

Retrospective

6

Sakyanun 202019

50 (25/25)

NA

NA

50 Gy/25 f

IMRT

Retrospective

6

Vikström 201128

34 (17/17)

NA

60

50 Gy/25 f

3D-CRT

Retrospective

6

Yamauchi 20208

170 (85/85)

NA

49.3

50 Gy/25 f

IMRT

Retrospective

7

Zhao-Feng 201820 (3D-CRT Group)

44 (22/22)

NA

48

50 Gy/25 f

3D-CRT

Retrospective

7

Zhao-Feng 201820 (IMRT group)

44 (22/22)

NA

48

50 Gy/25 f

IMRT

Retrospective

7

  1. DIBH deep inspiration breath hold, FB free breathing, NOS Newcastle–Ottawa Scale, VMAT volumetric modulated arc therapy, IMRT intensity-modulated radiation therapy, 3D-CRT 3-dimensional conformal radiotherapy, NA not available.