Figure 3 | Scientific Reports

Figure 3

From: Identification and subsequent validation of transcriptomic signature associated with metabolic status in endometrial cancer

Figure 3

Relative mRNA expression of DEGs in EC (N = 57) and reference endometrial tissue (N = 30). (A) SLC7A11; (B) SLC7A5; (C) RUNX1; (D) LAMA4; (E) COL6A3; (F) PDK1; (G) CCNA1; (H) ENO1; (I) PKM; (J) NR2F1; (K) NAALAD2. Each bar represents the geometric mean ± standard error of mean (SEM). Gene expression was normalized on both peptidylprolyl isomerase A and beta-actin housekeeping genes. Levels of significance difference (Mann–Whitney U-test) when compared with control: ***p < 0.001; ****p < 0.0001; (L) Validation of the discovered DEGs in EC cell lines by Genevestigator software (v.9.10.0).

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