Table 1 Characteristics of the studies.

From: Efficacy and safety of fecal microbiota transplantation in the treatment of ulcerative colitis: a systematic review and meta-analysis

Study

Year

Country

Patient type

FMT mode

Control mode

Delivery route

Donor type

Evaluation time

Total dose of FMT

Kedia et al.8

2022

India

Mild to moderate UC

FMT-AID

SMT

Colonoscopy

Multiple donors

Week 8

350.0 g

Sarbagili et al.9

2022

Israel

Active UC

FMT + UCED

UCED

Colonoscopy and enema

Single donor

Week 8

133.3 g

Haifer et al.10

2022

Australia

Active UC

FMT

Placebo

Oral capsules

Single donor

Week 8

102.9 g

Crothers et al.11

2021

United States

Mild to moderate UC

FMT

Placebo

Colonoscopy and oral capsules

Multiple donors

Week 12

90.0 g

Březina et al.12

2021

Czech Republic

Active left-sided UC

FMT

5-ASA

Enema

Single donor

Week 12

500.0 g

Pai et al.13

2021

Canada

Pediatric active UC

FMT

Placebo

Enema

Multiple donors

Week 30

600.0 g

Fang et al.14

2021

China

Recurrent active UC

FMT

5-ASA

Colonoscopy

Single donor

Week 8

50.0 g

Schierová et al.15

2020

Czech Republic

Active left-sided UC

FMT

5-ASA

Enema

Single donor

Week 12

500.0 g

Sood et al.16

2019

India

Active UC

FMT + SOC

Placebo + SOC

Colonoscopy

Single donor

Week 48

700.0 g

Costello et al.17

2019

Australia

Mild to moderate active UC

FMT

Autologous FMT

Colonoscopy and enema

Multiple donors

Week 8

100.0 g

Paramsothy et al.18

2017

Australia

Active UC

FMT

Placebo

Colonoscopy and enema

Multiple donors

Week 8

1537.5 g

Rossen et al.19

2015

The Netherlands

Mild to moderate active UC

FMT

Autologous FMT

Nasoduodenal tube

Single donor

Week 12

240.0 g

Moayyedi et al.20

2015

Canada

Active UC

FMT

Placebo

Enema

Single donor

Week 7

300.0 g

  1. FMT-AID, faecal microbiota transplantation with anti-inflammatory diet; SMT, standard medical therapy; UCED, ulcerative colitis exclusion diet; SOC, standard of care therapy.