Figure 2 | Scientific Reports

Figure 2

From: Challenging interpretation of germline TP53 variants based on the experience of a national comprehensive cancer centre

Figure 2

(a) Patient cohort and genetic testing outcome. (b) Localizations of the identified variants in the TP53 gene. (c,d) Age and probability of first tumour onset in LFS, phenotypic LFS, and attenuated LFS groups. (e) Age of first tumour onset according to variants found in NCI TP53 database. Green stars-attenuated LFS; red stars-LFS patients. (f) Number of tumours in the proband and probands’ families in LFS, phenotypic and attenuated LFS groups.

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