Figure 2 | Scientific Reports

Figure 2

From: RETRACTED ARTICLE: Targeting transforming growth factor beta (TGF-β) using Pirfenidone, a potential repurposing therapeutic strategy in colorectal cancer

Figure 2

PFD effects on migration. (a) Effect of PFD, 5FU, and PFD + 5FU on the migration of CRC model, representative pictures of the wound-healing assay in CT-26 and SW-480 cells in 24 h (4 × magnification). (b) Relative wound healing measures in CT-26 and SW-480 cells, in control and treated cells. (c) E-cadherin mRNA expression in CT-26 and SW-480 after 72 h. The cells were treated at the IC50 value of each drug. In the combination-treated group, the IC50s of both drugs were used. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

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