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Figure 1

From: Renal tubular function and morphology revealed in kidney without labeling using three-dimensional dynamic optical coherence tomography

Figure 1

Dynamic OCT imaging of a fresh normal mouse kidney for a 6 mm \(\times\) 6 mm field of view. Cross-sections from (a) scattering OCT, (c) LIV, and (e) Fast-DOCT imaging; (b, d, f) En face slices of the OCT, LIV, and Fast-DOCT images at the depth location indicated by the horizontal line in (a); (g) H &E stained histological micrograph; (h, j) magnified images of the LIV and Fast-DOCT cross-section at the region indicated by the rectangular box in (c, e); (i, k) magnified images of the LIV and Fast-DOCT en face slice at the region indicated by the rectangular box in (d, f). The arrowhead in (a) indicates the depth location of the histology (g). Arrowheads in (c) and (d) indicate the high LIV (green) signals and arrows in (d) represent pipe-like structures. The hyper Fast-DOCT spots in the cross-section and enface are indicated by arrowheads in (e, f, j, k). The black arrow in (g) indicates the glomerulus and the yellow arrows indicate the renal tubules of the kidney tissue. LIV log-intensity variance, Fast-DOCT fast dynamic OCT, H &E hematoxylin and eosin. Scale bar 500 \(\upmu\)m.

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