Figure 4 | Scientific Reports

Figure 4

From: Renal tubular function and morphology revealed in kidney without labeling using three-dimensional dynamic optical coherence tomography

Figure 4

Dynamic OCT imaging of a 1-week obstructed kidney model for 6 mm \(\times\) 6 mm field of view. Cross-sections from (a) scattering OCT, (c) LIV, and (e) Fast-DOCT imaging; (b, d, f) En face slices of the OCT, LIV, and Fast-DOCT images at the depth location indicated by the horizontal line in (a); (g, h) microscopic and macroscopic views of H &E stained histological micrograph; (i, j) magnified images of the LIV and Fast-DOCT cross-sections at the region indicated by the rectangular boxes in (c) and (e). The arrowhead in (a) indicates the depth location of the histology (g). The yellow-dot circles in (f) are artifacts caused by the strong reflection from the tissue surface. The white arrowheads in (c) and (d) represent a high-LIV superficial layer. The arrows in (i) and (j) show the collocation of high-LIV and hyper-Fast-DOCT spots. The blue arrow in (g) indicates a glomerulus and the black arrows indicate renal tubules of the kidney tissue. LIV log-intensity variance, Fast-DOCT fast dynamic OCT. Scale bar 1 mm.

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