Table 2 Change in ophthalmic parameters over 2-year atropine 0.01% treatment.

From: Age-related results over 2 years of the multicenter Spanish study of atropine 0.01% in childhood myopia progression

Variable

First year atropine 0.01% treatment (n = 81)

Baseline visit

12 months

Mean change

p-value

SE (mean ± SD, D)

− 3.57 ± 1.12

− 4.00 ± 1.14

− 0.42 ± 0.41

 < 0.001

AL (mean ± SD, mm)

24.56 ± 0.75

24.82 ± 0.77

0.25 ± 0.16

 < 0.001

AC (mean ± SD, mm)

3.79 ± 0.33

3.82 ± 0.30

0.02 ± 0.26

0.019

Pupil size (mean ± SD, mm)

5.63 ± 1.38

6.28 ± 1.09

0.66 ± 1.08

 < 0.001

Near VA (logMAR)

0.00 ± 0.02

0.00 ± 0.01

− 0.00 ± 0.02

0.853

Distance VA (logMAR)

0.00 ± 0.03

− 0.00 ± 0.04

− 0.01 ± 0.05

0.545

 

Second year atropine 0.01% treatment (n = 81)

12 months

24 months

Mean change

p-value

SE (mean ± SD, D)

− 4.00 ± 1.14

− 4.43 ± 1.23

− 0.45 ± 0.39

 < 0.001

AL (mean ± SD, mm)

24.56 ± 0.75

25.04 ± 0.79

0.23 ± 0.14

 < 0.001

AC (mean ± SD, mm)

3.82 ± 0.30

3.85 ± 0.26

0.02 ± 0.20

0.031

Pupil size (mean ± SD, mm)

6.28 ± 1.09

6.45 ± 0.99

0.14 ± 0.66

0.045

Near VA (logMAR)

0.00 ± 0.01

0.00 ± 0.02

− 0.00 ± 0.23

0.950

Distance VA (logMAR)

-0.00 ± 0.04

− 0.01 ± 0.03

− 0.00 ± 0.02

0.141

 

2 years atropine 0.01% treatment (n = 81)

Baseline visit

24 months

Mean change

p-value

SE (mean ± SD, D)

− 3.57 ± 1.12

− 4.43 ± 1.23

− 0.88 ± 0.60

 < 0.001

AL (mean ± SD, mm)

24.56 ± 0.75

25.04 ± 0.79

0.49 ± 0.25

 < 0.001

AC (mean ± SD, mm)

3.79 ± 0.33

3.85 ± 0.26

0.04 ± 0.27

0.004

Pupil size (mean ± SD, mm)

5.63 ± 1.38

6.45 ± 0.99

0.79 ± 1.21

 < 0.001

Near VA (logMAR)

0.00 ± 0.02

0.00 ± 0.02

− 0.00 ± 0.03

1.000

Distance VA (logMAR)

0.00 ± 0.03

− 0.01 ± 0.03

− 0.01 ± 0.04

0.010

  1. SE, spherical equivalent; SD, standard deviation; D, diopter; AL, Axial length; AC, anterior chamber; VA, visual acuity; logMAR, logarithm of minimun angle resolution.
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