Figure 4

Relation of the tissue particle count, tumor cell count (tcN) and area infiltrated by tumor (tiA) represented by 2D-scatterplots with side-histograms of the respective distributions. (A) The total count of tissue particles and the count of tumor-bearing tissue particles are interrelated (tumor-bearing ≤ total count; right-hand spread of datapoints). (B,C) The count of tissue fragments is only weakly correlated to tiA (r = 0.28, upper right) and to tcN (r = 0.20, lower left). (D) tiA and tcN show a strong linear correlation (r = 0.71).