Table 1 Baseline clinic-pathological characteristics.

From: Natural killer cell activity in metastatic castration resistant prostate cancer patients treated with enzalutamide

Mean age, years (range)

76 (54–89)

PS

 0

49

 1

24

 2

4

 N/A

10

Pathology

 Adenocarcinoma

87

ISUP

 I

8

 II

7

 III

18

 IV

19

 V

33

 N/A

2

Type of initial management

 RARP

6

 RT

9

 DOC upfront

15

Time from initial management to 1. cycle enzalutamide, mo, median (range)

25 (4–231)

 RARP

135 (18–231)

 RT

89 (26–168)

 DOC upfront

17 (4–25)

Type of castration treatment

 Medical

81

 Medical then surgical

6

 Median PSA level, ng/mL (range)

50 (1–396)

Site of metastases*

 Bone

73

 LN

39

 Lung

5

 Others

3

Time to mCRPC, mo, median (range)

68 (8–238)

Follow-up, mo, median (range)

39 (14–62)

Time to BP, mo, median (range)

7 (1–47)

Time to RP, mo, median (range)

20 (2–53)

Death

42

Synchronic cancer

2

Previous Cancer

7

Auto-immune disease

6

  1. ADT anti-deprivation therapy, BP biochemical progression, DOC docetaxel, Dx diagnosis, ISUP International Society of Urological Pathology, LN lymph node, mCRPC metastatic castration resistant prostate cancer, mo month, PSA prostate specific antigen, PS performance status, RARP robot assisted radical prostatectomy, RP radiological progression, RT radiotherapy.
  2. *Some patients have metastases to more than one site.