Table 4 Association between change in IFNγ plasma level and clinical outcomes in the four subgroups after adjustment for baseline ISUP, baseline neutrophil count, and NLR:

From: Natural killer cell activity in metastatic castration resistant prostate cancer patients treated with enzalutamide

Groups

OS

rPFS

TTT

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

1

1

 

1

 

1

 

2

2.78 (0.57–13.59)

0.206

4.30 (1.09–16.93)

0.037

6.82 (1.55–30.03)

0.011

3

1.09 (0.34–3.50)

0.891

1.49 (0.55–3.99)

0.432

1.13 (0.39–3.26)

0.816

4

1.24 (0.35–4.47)

0.739

1.58 (0.63–3.94)

0.330

1.53 (0.59–3.92)

0.380