Figure 1

Body weight, body composition and energy expenditure of mice on Western diets. (A) the composition of FAs in terms of saturation and specific fatty acid species in WD-B and WD-CO diets. (B) experimental timeline and design aimed to induce atherosclerosis via Ldlr−/− ASO (C) Western blot for Ldlr expression in liver tissue from untreated and Ldlr ASO treated mice. (D) time course of body weight change. (E) Percentage of fat mass. (F) Percentage of lean mass. (G) Whole-body oxygen consumption. (H) Whole-body respiratory exchange ratio. Data represented as mean ± SEM with n = 8–10 (D–H).