Figure 2

The impact of WD-B and WD-CO on atherosclerotic development in Ldlr ASO mice. (A) Representative images depicting plaque formation (white arrow heads) in aortic arch. (B) Representative images of en face aorta stained with Sudan IV (bright red) which denoted atherosclerotic lesions. (C) Percentage of lesion area over total aortic area (total), aortic arch (arch) and innominate artery (arteries). Data represented as mean ± SEM with n = 8–10 (C). Statistical significance was determined by Student’s t-test (*p < 0.05, **p < 0.01, and ***p < 0.001).