Figure 4 | Scientific Reports

Figure 4

From: Replacement of saturated fatty acids with linoleic acid in western diet attenuates atherosclerosis in a mouse model with inducible ablation of hepatic LDL receptor

Figure 4

Liver mass, lipid composition, and FA oxidation in Ldlr ASO mice on WD-B and WD-CO. (A) Percentage of liver mass compared to body mass. (B) Fasting TG levels in liver tissue. (C) Representative images of H&E-stained liver sections. (D) Fasting plasma concentration of β-hydroxybutyrate. (E) Hepatic mRNA expression of FA oxidative associated genes by qPCR. (F) Hepatic total (free and esterified) cholesterol levels. (G) Hepatic mRNA expression of cholesterol and bile metabolism associated genes by qPCR. Data represented as mean ± SEM with n = 8–10 (A–B, C–G). Statistical significance was determined by Student’s t-test (*p < 0.05 and **p < 0.01).

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