Figure 2
From: Catheter-associated Mycobacterium intracellulare biofilm infection in C3HeB/FeJ mice
Bioluminescent in vivo imaging of Lux system in mice. (A) Representative series of bacterial bioluminescence signals on a color scale superimposed on a grayscale image of a single mouse from untreated (above) and treated (below) with antimicrobials at the indicated time points. The uninfected control mouse is shown at the upper right. The color scale shows photons per second per square centimeter per steradian (p/s/cm2/sr). (B) The sagittal (left) and coronal (right) CT images from representative M. intracellulare-infected mouse at 22 dpi with or without antimicrobial treatment. Dotted circles show the visualized catheter in the peritoneal cavity. (C) Calculation and plot of bioluminescent intensity at each time point expressed in photons per second (p/s). Statistical analysis by ANOVA with Sidack’s multiple comparison test: *P < 0.05, ****P < 0.0001.
