Table 7 Correlation between the pathological findings and CKα expression.

From: Correlation between choline kinase alpha expression and 11C-choline accumulation in breast cancer using positron emission tomography/computed tomography: a retrospective study

 

CKα expression

P-value

0

1

2

Invasive component

Present

11 (20)

15 (27)

22 (39)

0.001

Absent

7 (13)

1 (1.8)

0 (0)

Lymphatic invasion

Present

13 (23)

9 (16)

12 (21)

0.48

Absent

5 (8.9)

7 (13)

10 (18)

Histologic grade

1

2 (3.6)

1 (1.8)

0 (0)

0.60

2

8 (14)

9 (16)

12 (21)

3

8 (14)

6 (11)

10 (18)

Nuclear grade

1

5 (8.9)

6 (11)

4 (7.1)

0.78

2

5 (8.9)

4 (7.1)

7 (13)

3

8 (14)

6 (11)

11 (20)

Nuclear atypia

1

1 (1.8)

1 (1.8)

0 (0)

0.71

2

9 (16)

9 (16)

10 (18)

3

8 (14)

6 (11)

12 (21)

Mitosis

1

8 (14)

12 (21)

10 (18)

 < 0.0001

2

10 (18)

1 (1.8)

0 (0)

3

0 (0)

3 (5.4)

12 (21)

Extensive intraductal components

Present

9 (16)

3 (5.4)

2 (3.6)

0.01

Absent

9 (16)

13 (23)

20 (36)

Necrosis

Present

8 (14)

6 (11)

10 (18)

0.88

Absent

10 (18)

10 (18)

12 (21)

Fat invasion

Present

7 (13)

9 (16)

17 (30)

0.05

Absent

11 (20)

7 (13)

5 (8.9)

Cutaneous invasion

Present

1 (1.8)

2 (3.6)

2 (3.6)

0.78

Absent

17 (30)

14 (25)

20 (36)

Muscular invasion

Present

1 (1.8)

1 (1.8)

0 (0)

0.51

Absent

17 (30)

15 (27)

22 (39)

HER-2 receptor

0

7 (13)

6 (11)

11 (20)

0.12

1

10 (18)

4 (7.1)

7 (13)

3

1 (1.8)

6 (11)

4 (7.1)

Oestrogen receptor

Positive

18 (32)

10 (18)

15 (27)

0.02

Negative

0 (0)

6 (11)

7 (13)

Progesterone receptor

Positive

18 (32)

11 (20)

11 (20)

0.002

Negative

0 (0)

5 (8.9)

11 (20)

  1. Data are presented as the number of cases. The data in parentheses are presented as percentages.
  2. HER-2 Human epidermal growth factor-2; CKα Choline kinase alpha.