Table 8 Correlation between the pathological findings and CKα expression (CKα 0–1 vs. 2).

From: Correlation between choline kinase alpha expression and 11C-choline accumulation in breast cancer using positron emission tomography/computed tomography: a retrospective study

 

CKαexpression

P-value

0–1

2

Invasive component

Present

26 (46)

22 (39)

0.01

Absent

8 (14)

0 (0)

Lymphatic invasion

Present

22 (39)

12 (21)

0.45

Absent

12 (21)

10 (18)

Histologic grade

1

3 (5.4)

0 (0)

0.36

2

17 (30)

12 (21)

3

14 (25)

10 (18)

Nuclear grade

1

11 (20)

4 (7.1)

0.51

2

9 (16)

7 (13)

3

14 (25)

11 (20)

Nuclear atypia

1

2 (3.6)

0 (0)

0.38

2

18 (32)

10 (18)

3

14 (25)

12 (21)

Mitosis

1

20 (36)

10 (18)

 < 0.0001

2

11 (20)

0 (0)

3

3 (5.4)

12 (21)

Extensive intraductal components

Present

12 (21)

2 (3.6)

0.03

Absent

22 (39)

20 (36)

Necrosis

Present

14 (25)

10 (18)

0.75

Absent

20 (36)

12 (21)

Fat invasion

Present

16 (29)

17 (30)

0.03

Absent

18 (32)

5 (8.9)

Cutaneous invasion

Present

3 (5.4)

2 (3.6)

0.97

Absent

31 (55)

20 (36)

Muscular invasion

Present

2 (3.6)

0 (0)

0.25

Absent

32 (57)

22 (39)

HER-2

0

13 (23)

11 (20)

0.68

1

14 (25)

7 (13)

3

7 (13)

4 (7.1)

Oestrogen receptor

Positive

28 (50)

15 (27)

0.22

Negative

6 (11)

7 (13)

Progesterone receptor

Positive

29 (52)

11 (20)

0.004

Negative

5 (8.9)

11 (20)

  1. Data are presented as the number of cases. The data in parentheses are presented as percentages.
  2. HER-2 Human epidermal growth factor-2; CKα Choline kinase alpha.