Table 8 Correlation between the pathological findings and CKα expression (CKα 0–1 vs. 2).
CKαexpression | P-value | ||
---|---|---|---|
0–1 | 2 | ||
Invasive component | |||
Present | 26 (46) | 22 (39) | 0.01 |
Absent | 8 (14) | 0 (0) | |
Lymphatic invasion | |||
Present | 22 (39) | 12 (21) | 0.45 |
Absent | 12 (21) | 10 (18) | |
Histologic grade | |||
1 | 3 (5.4) | 0 (0) | 0.36 |
2 | 17 (30) | 12 (21) | |
3 | 14 (25) | 10 (18) | |
Nuclear grade | |||
1 | 11 (20) | 4 (7.1) | 0.51 |
2 | 9 (16) | 7 (13) | |
3 | 14 (25) | 11 (20) | |
Nuclear atypia | |||
1 | 2 (3.6) | 0 (0) | 0.38 |
2 | 18 (32) | 10 (18) | |
3 | 14 (25) | 12 (21) | |
Mitosis | |||
1 | 20 (36) | 10 (18) | < 0.0001 |
2 | 11 (20) | 0 (0) | |
3 | 3 (5.4) | 12 (21) | |
Extensive intraductal components | |||
Present | 12 (21) | 2 (3.6) | 0.03 |
Absent | 22 (39) | 20 (36) | |
Necrosis | |||
Present | 14 (25) | 10 (18) | 0.75 |
Absent | 20 (36) | 12 (21) | |
Fat invasion | |||
Present | 16 (29) | 17 (30) | 0.03 |
Absent | 18 (32) | 5 (8.9) | |
Cutaneous invasion | |||
Present | 3 (5.4) | 2 (3.6) | 0.97 |
Absent | 31 (55) | 20 (36) | |
Muscular invasion | |||
Present | 2 (3.6) | 0 (0) | 0.25 |
Absent | 32 (57) | 22 (39) | |
HER-2 | |||
0 | 13 (23) | 11 (20) | 0.68 |
1 | 14 (25) | 7 (13) | |
3 | 7 (13) | 4 (7.1) | |
Oestrogen receptor | |||
Positive | 28 (50) | 15 (27) | 0.22 |
Negative | 6 (11) | 7 (13) | |
Progesterone receptor | |||
Positive | 29 (52) | 11 (20) | 0.004 |
Negative | 5 (8.9) | 11 (20) |