Table 5 Significant genetic risk factors for atorvastatin associated muscle symptoms adjusted for the non-genetic covariates.

From: Genetic polymorphisms in ABCB1 are correlated with the increased risk of atorvastatin-induced muscle side effects: a cross-sectional study

Variable

OR crude (95% CI)a

p valuea

OR adjusted (95% CI)b

p valueb

TT vs. CT + CC

1236C > T

3.155 (1.178–8.868)

0.0240

4.292 (1.481–13.69)

0.0093

T(A)/T(A) vs. GT(A) + GG

2677G > T/A

5.943 (2.03–20.01)

0.0019

5.897 (1.975–20.06)

0.0023

TT vs. CT + CC

3435C > T

3.457 (1.352–9.25)

0.0107

3.547 (1.342–9.908)

0.0122

TTT/TTT vs. others

7.097 (2.009–33.33)

0.0047

9.234 (2.399–47.84)

0.0028

  1. OR odds ratio.
  2. aUnivariable logistic regression.
  3. bMultivariable logistic regression.
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