Figure 3
Non-competitive auto-inhibition of functional response. Dots, functional response to an agonist (KI = 1, EMAX = 1, RT = 1, KA = 10−6 M) in the model of non-competitive autoinhibition according to Eq. (15). Values of operational efficacies τ are indicated in the legend. Full lines, left, Black & Leff equation (Eq. (7)), right, Hill equation (Eq. (10)) fitted to the data. Parameter estimates are in Table 1.
