Figure 2
From: An in vitro model and the underlying pathways of sinonasal inverted papilloma development
EGFR (ERBB1) exon 20 mutation induces inverted papilloma formation. (A) The effect of a specific EGFR exon 20 mutation on sinonasal inverted papilloma formation was investigated by organotypic raft culture. (B) H&E staining of a primary tumor where iIP4 cell are derived. Black arrows indicated an inverted growth pattern observed in the raft culture.
