Figure 1

Examples of CDH16 immunostaining in normal thyroid and papillary Thyroid cancer (PTC). (A) Representative section of normal thyroid tissue showing strong positive membrane expression of CDH16 in the follicular cells. (B) PTC tissue showing positive staining for CDH16 and (C) another PTC tissue showing negative staining for CDH16 with adjacent normal tissue showing positive expression. (20 X/0.70 objective on an Olympus BX 51 microscope (Olympus America Inc, Center Valley, PA, USA)).