Figure 2

Electric field modelling in lesioned and non-lesioned brains using M1 as an example. (A) Electric field (E-field) magnitude image for M1 montage for the non-lesioned ‘healthy’ brain. M1 outlined in yellow; electrode locations outlined in red (anode) and blue (cathode). (B) E-field magnitude image for same montage but in the lesioned brain (filled white circle; RAI lesion, distance 1 mm, size 12 mm, conductivity 1.2S/m). (C) Difference image (lesioned minus non-lesioned brain). Note the strong increases and decreases in E-field around the lesion, with differences of approximately ± 0.1 V/m. (D) E-field direction in the non-lesioned brain given as vectors (green). Vector length denotes E-field magnitude (V/m). (E) Calculation of angle between the lesion direction (black line) and the average direction of E-field within the grey matter of the ROI (orange line).