Figure 2

Identification of IRGPM. (A)Volcano plot for differentially expressed genes between normal patients and ccRCC based on TCGA-KIRC cohort. (B) Venn diagram of DEGs and IRGs. DEGs: Differentially expressed genes, IRGs: immune-related genes. (C) KEGG Analysis of the top 10 enrichment pathways. (D) GO enrichment analysis of 679 DEIRGs in ccRCC. BP, CC, and MF indicates molecular function, cellular constituents, and biological process, respectively. DEIRGs indicates differentially expressed immune-related genes. (E) GSEA revealed several significantly enriched oncological signatures. The upper part of the plot shows the enrichment score; the lower part of the plot shows the ranked list metric for the gene set.