Figure 2 | Scientific Reports

Figure 2

From: Identification and validation of novel prognostic signatures based on m5C methylation patterns and tumor EMT profiles in head and neck squamous cell carcinoma

Figure 2

Characterization of m5C methylation patterns in HNSCC. (a) Relative changes in the cumulative distribution function (CDF) area for k = 2–6; (b) Consensus clustering cumulative distribution function (CDF) for k = 2–6; (c) Consensus clustering matrix for k = 2, and the color legend for consistency is on the right, indicating that the higher the consistency of the data, the bluer the color; (d) Principal component analysis (PCA) used to distinguish two different m5C methylation modification patterns; (e) GSVA demonstrated differential m5C scores between the two m5C methylation clusters; (f) Kaplan–Meier curves of the two clusters. g: Expression levels of m5C regulatory genes in the two clusters. The heatmap was constructed via the R package ggplot2.

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