Table 2 Count of red blood cells (RBC), white blood cells (WBC), platelets (PLT), serum glutamic-oxaloacetic transaminase (SGOT) and serum glutamic-pyruvic transaminase in mice of all groups (SGPT). n = 9—10 for each group.

From: Safety assessment, radioiodination and preclinical evaluation of antinuclear antibody as novel medication for prostate cancer in mouse xenograft model

Parameters/References41

Group I (3 days)

Group II (30 days)

RBC (× 1012/L)

7.8–10.6 (× 1012/L)

 Control

8.11 ± 0.89

11.69 ± 1.02

 5 μg ANA

7.37 ± 0.99

10.20 ± 0.72

 50 μg ANA

5.76 ± 0.94*

8.48 ± 0.59*

WBC (× 109/L)

2–10 (× 109/L)

 Control

4.01 ± 2.11

4.28 ± 0.63

 5 μg ANA

5.72 ± 2.58

5.66 ± 1.42

 50 μg ANA

5.99 ± 1.66

7.11 ± 2.55*

PLT (× 103/L)

900–1600 (× 103/L)#

 Control

858.20 ± 242.59

854.60 ± 211.54

 5 μg ANA

874.00 ± 482.32

979.40 ± 344.28

 50 μg ANA

535.00 ± 233.93*

592.00 ± 106.81*

SGOT (U/L)

54–298 (U/L)#

 Control

133.50 ± 73.64

110.80 ± 38.67

 5 μg ANA

167.20 ± 137.57

157.60 ± 63.22

 50 μg ANA

367.00 ± 264.88*

183.20 ± 89.37

SGPT (U/L)

17–77 U/L#

 Control

56.60 ± 41.62

41.00 ± 12.39

 5 μg ANA

89.06 ± 64.69

55.80 ± 20.10

 50 μg ANA

51.70 ± 23.28

49.10 ± 11.51

  1. (#) Mouse biochemistry normal ranges are referred from en.wikivet.net reference. Within a column of the same hematological parameters, those marked with an asterisk (*) are different from the corresponding control group (P < 0.05). Within a column of the same biochemical parameter, those marked with an asterisk (*) are different from the corresponding control group (P < 0.05).
Back to article page