Figure 2

Effect of DSHT on the release of NO and PGE2 in LPS-stimulated RAW 264.7 macrophages. Content of NO (A) and PGE2 (B) on the RAW 264.7 cells treated with the indicated concentration of DSHT (25–400 μg/mL), L-NMMA (100 μM), and indomethacin (5.6 nM) and stimulated with or without LPS (1 μg/mL) for 24 h. Data are presented as mean ± SD (n = 3). ###p < 0.001 vs. untreated control; **p < 0.01 and ***p < 0.001 vs LPS.