Table 1 Demographic and clinical features of the evaluated patients in retrospective phase.
Whole cohort, retrospective phase | Patients with atlantoaxial joint involvement, retrospective phase | |
---|---|---|
Patients | 717 | 15 |
Gender (female/male) | 56.6%/43.4% | 87.7%/13.3% |
Age, mean ± SD, years | 64.7 ± 12.3 | 58.0 ± 11.8 |
Disease duration at the first observation, median (range), years | 10 (28) | 6 (7) |
< 1 year | 40.6% | 40.0% |
Between 1 and 5 years | 34.0% | 33.3% |
Between 5 and 10 years | 25.4% | 26.7% |
RF and/or ACPA | 68.3% | 100% |
Extra-articular disease | 6.7% | 40.0% |
Smoking habit | 34.4% | 46.6% |
GCs low dose | 78.2% | 0.0% |
GCs high dose | 12.6% | 100.0% |
MTX | 71.9% | 100.0% |
HCQ | 25.9% | 14.2% |
LEF | 13.1% | 0.0% |
SSZ | 7.1% | 0.0% |
Biologic DMARDs | 43.5% | 60.0% |
TNFis | 26.2% | 60.0% |
Non-TNFis | 17.3% | 0.0% |
Targeted synthetic DMARDs | 2.5% | 0.0% |