Figure 3

Bidirectional causal relationship between genetically predicted IL17 and cisplatin-induced hearing loss in children. (A) Genetically predicted IL17 on the risk of cisplatin-induced hearing loss. (B) The scatter plots in relation to IL17 and the associated risk of cisplatin-induced hearing loss in children. (C) Leave-one-out analysis of Mendelian randomization (MR) estimates of genetic risk of IL17 on cisplatin-induced hearing loss in children. (D) Genetically predicted cisplatin-induced hearing loss on the level of circulating IL17. IL-17 interleukin-17, OR odds ratio, CI confidence interval.