Table 2 Synthesis table of chaperon and lipochaperon activities of Lo18 or modified proteins link to their secondary structure modifications. The presence or absence of Lo18 serves as a reference for these activities, where “++” indicates a high level, “+” denotes a moderate level, and “–” signifies no activity.

From: Significant influence of four highly conserved amino-acids in lipochaperon-active sHsps on the structure and functions of the Lo18 protein

 

Lo18

E60K

T79V

G82V

R99D

Ø Lo18

Chaperon activity

++

+

+

++

Lipochaperon activity slope

++

+

+

++

Lipochaperon activity shock

++

+

++

Membrane rigidification by protein addition

++

++

++

Membrane insertion (SRCD)

++

+

+

α-Helix

++

+

++

 

β-Sheet

++

+

+

 

Turn

=

=

=

=

=

 

Other structure

=

=

=

=

=