Table 1 Incidence of ATD-induced leukopenia and G-CSF administration.
From: Antithyroid drug-induced leukopenia and G-CSF administration: a long-term cohort study
Patients receiving an ATD (MMI or PTU) | Patients with leukopenia | Patients without leukopenia | P-value | Patients with G-CSF administration | Patients with leukemia without G-CSF administration | P-value | |
|---|---|---|---|---|---|---|---|
Number of patients | 12,491 | 168 | 12,323 | 38 | 130 | ||
Age (years, median) (years, 95% CI) | 58 (55.5 to 56.1) | 57 (51.8 to 56.4) | 58 (55.5 to 56.1) | P = 0.20 | 60 (52.4 to 61.8) | 53 (50.5 to 55.9) | P = 0.24 |
Sex (F:M) | (3.0: 1) | (2.7: 1) | (2.5 : 1) | (2.8 : 1) | |||
Female | 9335 | 123 (1.3%) | 9212 (98.7%) | P = 0.66 | 27 (0.3%) | 96 (1.0%) | P = 0.84 |
Male | 3156 | 45 (1.4%) | 3111 (98.6%) | 11 (0.3%) | 34 (1.1%) | ||
Observation period (days, 95% CI) | 833 (822 to 844) |
