Figure 11
From: Morphine aggravates inflammatory, behavioral, and hippocampal structural deficits in septic rats
Effect of µ-opioid receptor blockade by naloxone (0.5 mg/kg, s.c.) on morphine (7 mg/kg, s.c.) evoked alternations in (A) SBP, (B) plasma IL1β, (C) distance travelled, (D) recognition index, (E) horizontal movements, (F) number of crossings recorded in the new object recognition test in sham rats. Data were expressed as mean ± S.E.M (n = 5–9). One-way ANOVA followed by the Tukey’s post hoc test was used to measure statistical significance *P < 0.05 vs. Saline, +P < 0.05 vs. Morphine group.
