Figure 5
From: Morphine aggravates inflammatory, behavioral, and hippocampal structural deficits in septic rats
Behavioral and cognitive effects of morphine (7 mg/kg, s.c.) on CLP induced sepsis in rats using Morris Water Maze (A) time spent on platform quadrant, (B) distance travelled, (C) number of crossings, (D) escape latency, and the corresponding Pearson correlation with the systolic blood pressure, (E) time spent of platform quadrant, (F) distance travelled, (G) number of crossings, (H) escape latency. Data were expressed as mean ± S.E.M (n = 6–7). One-way ANOVA followed by the Tukey’s post hoc test was used to measure statistical significance. *P < 0.05 vs. Sham-saline, +P < 0.05 vs. CLP-saline, #P < 0.05 vs. Sham-morphine.
