Figure 4
From: Comprehensive characterization of TGFB1 across hematological malignancies
The relation between TGFB1 expression with tumor microenvironment in hematological malignancies. (A) Bubble chart depicting the association between TGFB1 expression and 29 TME signature scores across main blood cancer types in Hemap. (B–E) Radar chart showing correlations of TGFB1 expression with immune, stromal, and cytolytic score across main cancer types in Hemap. Asterisks represents the statistical p value (*p < 0.05; **p < 0.01; ***p < 0.001). (F) Pie charts showing correlations of TGFB1 expression with immune cell infiltration deconvoluted using CIBERSORT or MCP-counter algorithms in Hemap. Each pie chart indicates the correlation with each signature score in each cancer type. (G) Heatmap showing the expression levels of TGFB1 in annotated cell types from scRNA-seq datasets.
