Figure 5 | Scientific Reports

Figure 5

From: Mediating oxidative stress through the Palbociclib/miR-141-3p/STAT4 axis in osteoporosis: a bioinformatics and experimental validation study

Figure 5

Identification of hub genes, correlation analysis of cytokines, and Mendelian randomization analysis. (A) The Venn diagram showing the screening of the three hub genes. (B) Violin plot of the expression of the three hub genes in the two groups. (C) Heat map of the correlation between the three hub genes and inflammatory factors, with correlation coefficient in the upper left corner and p-value in the lower right corner. (D) Forest plot of the Mendelian randomization analysis between cytokines and osteoporosis. (E) Forest plot of Mendelian randomization analysis between IL-2 and osteoporosis. (F) Forest plot of Mendelian randomization analysis between IL-7 and osteoporosis (***p < 0.001, **p < 0.01, *p < 0.05).

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