Table 1 Association analysis for the risk HLA-DQB1 allele of CS incidence.

From: Human leukocyte antigen-DQ risk heterodimeric haplotypes of left ventricular dysfunction in cardiac sarcoidosis: an autoimmune view of its role

Allele

Cardiac sarcoidosis (n = 68)

Control (n = 311)

P_adj

DQB1*06:01

38 (56%)

105 (34%)

0.096*

DQB1*05:01

1 (1.5%)

33 (11%)

n.s

DQB1*04:01

21 (31%)

68 (22%)

n.s

DQB1*05:03

1 (1.5%)

17 (5.5%)

n.s

DQB1*04:02

8 (12%)

25 (8.0%)

n.s

DQB1*06:02

7 (10%)

46 (15%)

n.s

DQB1*03:02

11 (16%)

57 (18%)

n.s

DQB1*06:03

2 (2.9%)

14 (4.5%)

n.s

DQB1*03:03

20 (29%)

100 (32%)

n.s

DQB1*03:01

15 (22%)

69 (22%)

n.s

DQB1*06:04

5 (7.4%)

26 (8.4%)

n.s

  1. n.s. no significant difference.
  2. *Significance after the correction for multiple testing (Bonferroni correction); P_adj. < 0.05.
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