Table 2 Association analysis between the risk HLA allele of DQB1*06:01 and clinical phenotypes.

From: Human leukocyte antigen-DQ risk heterodimeric haplotypes of left ventricular dysfunction in cardiac sarcoidosis: an autoimmune view of its role

 

With DQB1*06:01 (n = 38)

Without DQB1*06:01 (n = 30)

P

Clinical characteristics

Age of onset (years)

64 [56–72]

60 [52–69]

0.42

Gender (female)

23 (61%)

20 (67%)

0.62

Clinical phenotypes

 CAVB

18 (47%)

12 (40%)

0.63

 VT or VF

16 (42%)

9 (30%)

0.33

  Sustained VT or VF

10 (26%)

7 (23%)

1.00

 LVEF (%)

45 [33–57]

46 [35–63]

0.60

  Low LVEF

24 (63%)

17 (57%)

0.63

 Cardiac device implantation

29 (76%)

20 (67%)

0.42

 Successful corticosteroid therapy

15 (44%)

6 (27%)

0.26

  1. CAVB complete atrioventricular block, VT ventricular tachycardia, VF ventricular fibrillation, LVEF left ventricular ejection fraction, Low LVEF the patients with LVEF < 50% in the echocardiography at the enrolment.
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