Figure 3

Representative images of myocardial ultra-structure ultra-images showing myocardiual fibers and mitochondria taken with a transmission electron microscope. (× 20,000 magnification, scale bar 1 μm, mitochondria denoted by arrows). Images are from the following groups: C, D, DE, DM, DME. Myocardial mitochondria from diabetic myocardium are characterized by mitochondrial swelling, loss of crest, and vacuolization. C control, D diabetic, DE diabetic exercise, DM diabetic MOTS-c treatment, DME diabetic exercise combined with MOTS-c treatment. The number of samples was 3 in each group.