Figure 4
From: Superiority of systemic bleomycin to intradermal HOCl for the study of interstitial lung disease
HOCl injections do not induce lung inflammation. (a) Total and differential cell count from BALF of HOCl and PBS -injected mice (n = 9–15). Quantification of total numbers of (b) eosinophils (SiglecF+, CD11b+), (c) alveolar macrophages (SiglecF+, CD11b−), (d) neutrophils (SiglecF−, CD11b+, Ly6G+), (e) macrophages (SiglecF−,CD11b+, Ly6G−, F4/80+, Ly6C+/−), (f) inflammatory monocytes (SiglecF−, CD11b+, Ly6G−, F4/80−, Ly6C+), (g) inflammatory monocyte-derived macrophages (SiglecF−, CD11b+, F4/80+, Ly6C+), and (h) interstitial macrophages (SiglecF−, CD11b+, F4/80+, Ly6Clow/neg) (n = 6). Data are represented as mean ± SEM from 2 to 4 experiments Data were analyzed using Two-way ANOVA (a) and Mann–Whitney U test (b–h). ns not significant.
