Figure 9

(A) RMSD of Cα atoms of PPAR-γ in apo form (red line) and in complex with compound 5c (blue line) or nTZDpa (sky blue line); (B) RMSF of Cα atoms of PPAR-γ in apo form (red line) and in complex with compound 5c (blue line) or nTZDpa (sky blue line) during 150 ns MD simulation.