Figure 5
(A) Volcano plot of differential KEGG orthologs (KOs) abundance, between samples from LS participants and samples from non-LS participants. Red dots indicate differentially abundant bacteria with a p-value < 0.05 and log2 fold change > 1.5 and < − 1.5, respectively (detected by the DeSeq2 algorithm (Wald test, p < 0.05)). (B) Volcano plot of differential KOs abundance, between samples from LS participants with and without history cancer. Red dots indicate differentially abundant bacteria with a p-value < 0.05 and log2 fold change > 1.5 and < − 1.5, respectively (detected by the DeSeq2 algorithm (Wald test, p < 0.05)). (C) Venn diagram showing the number and percentages of KOs enriched in LS participants, enriched in LS with a history of cancer, and enriched in both groups.
