Figure 5 | Scientific Reports

Figure 5

From: IGSF6 is a novel biomarker to evaluate immune infiltration in mismatch repair-proficient colorectal cancer

Figure 5

High IGSF6 expression is benefit from chemotherapy. (A) Representative micrographs of CD4+ T cells, CD8+ T cells, CD68+ macrophage cells and IGSF6 staining from endoscopic pathological tumor specimens before pMMR patients underwent chemotherapy, n = 21. (B) Quantification of the score for CD4+ T cells, CD8+ T cells, CD68+ macrophage cells and IGSF6 staining from chemosensitive CRC versus chemoresistance CRC by IHC assay, n = 21. pMMR, mismatch repair (MMR) proficiency; dMMR, mismatch repair (MMR) deficient. *p < 0.05, ***p < 0.001, ****p < 0.0001.

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