Table 1 Participant characteristics.
From: Relationship between klotho and physical function in healthy aging
Characteristics | 20–34 years n = 20 | 35–49 years n = 20 | 50–64 years n = 20 | 65 + years n = 20 | P-valuea |
|---|---|---|---|---|---|
Male, n (%) | 10 (50) | 10 (50) | 10 (50) | 10 (50) | 1.00 |
Age, years | 25.0 (22.0–29.2) | 43.0 (38.0–47.0)*‡ | 55.0 (52.0–60.5)*† | 70.5 (65.8–75.5)*†‡ | < 0.001 |
Height, cm | 172.0 (10.1) | 172.9 (9.1) | 170.7 (9.1) | 167.8 (7.2) | 0.30 |
Weight, kg | 72.6 (10.4) | 82.2 (12.1) | 79.3 (11.6) | 78.5 (16.6) | 0.13 |
BMI, kg/m2 | 24.4 (22.3–25.6) | 26.7 (24.2–30.8) | 26.8 (24.8–29.7) | 26.5 (24.2–29.4) | 0.06 |
Body Fat, % | 25.9 (11.9) | 29.0 (11.0) | 32.6 (11.2) | 34.5 (10.0) | 0.08 |
Fat Mass, kg | 14.1 (11.0–21.9) | 20.4 (14.2–26.0) | 19.4 (17.4–29.0) | 23.2 (19.4–28.4)* | 0.035 |
Lean Mass, kg | 43.4 (39.0–59.1) | 50.0 (44.7–57.4) | 47.2 (37.5–52.3) | 47.9 (36.8–53.0) | 0.40 |
Appendicular Lean Mass, kg/m2 | 7.8 (1.5) | 8.2 (0.9) | 7.8 (1.6) | 7.7 (1.3) | 0.72 |
Total BMD, g/cm2 | 1.03 (0.14) | 1.05 (0.12) | 0.97 (0.11) | 0.91 (0.12)*† | 0.004 |
Spine (L1-L4) BMD T-Score | − 0.14 (1.12) | 0.17 (1.18) | − 0.18 (0.96) | − 0.43 (1.26) | 0.48 |
Total Hip BMD T-Score | 0.37 (1.14) | 0.00 (1.25) | − 0.92 (1.23)* | − 1.41 (1.04)*† | < 0.001 |
Femoral Neck BMD T-Score | 0.19 (1.56) | − 0.51 (1.04) | − 1.23 (1.25)* | − 2.01 (0.95)*† | < 0.001 |
Klotho, pg/mL | 916.1 (284.8) | 829.6 (239.2) | 722.6 (190.5)* | 703.0 (189.3)* | 0.015 |
