Figure 3 | Scientific Reports

Figure 3

From: Comparative analysis identifies genetic and molecular factors associated with prognostic clusters of PANoptosis in glioma, kidney and melanoma cancer

Figure 3

Comparison of cell type fractions and cell type activation between PANoptosis High versus PANoptosis Low groups for LGG, KIRC and SKCM. (A) Cell type fractions in PANoptosis High and PANoptosis Low clusters for LGG, KIRC and SKCM cancers estimated using quanTIseq deconvolution method on bulk RNA-Seq gene expression profiles. (B) Heatmap of enrichment (activation) values for cell type specific immune-signature using the ssGSEA method. The difference in activity profiles of cell types between PANoptosis High versus PANoptosis Low samples were highlighted as ∆Activity, and significance in difference was estimated using a Wilcoxon rank-sum test with ***P-value < 1e−3. Samples from the PANoptosis High group are depicted below the red bar and samples from the PANoptosis Low group are depicted below the blue bar.

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