Table 2 ROBINS-I (risk of bias judgements in non-randomized studies of interventions).

From: Effects of therapeutic exercise on the motor function of adults with Down syndrome: a systematic review and meta-analysis

 

Confounding

Selection of participants

Classification of interventions

Deviations from intended interventions

Missing data

Measurement of outcomes

Selection of reported results

Overall

Davis y Sinning 198733

Moderate

Low

Moderate

Low

Low

Serious

Low

Serious

Aguiar et al. 200827

Low

Low

Low

Low

Moderate

Moderate

Moderate

Moderate

Cowley et al. 20119

Moderate

Low

Low

Low

Moderate

Serious

Low

Serious

Mendonca et al. 201115

Low

Low

Low

Low

Moderate

Moderate

Low

Moderate

Boer y de Beer 20192

Low

Low

Low

Low

Low

Moderate

Low

Moderate

Tsimaras V et al. 200430

Low

Low

Low

Low

Low

Moderate

Low

Moderate

Post E et al. 202231

Moderate

Low

Low

low

low

Serious

Low

Serious

  1. Low comparable to a well-performed randomized trial; Moderate sound for a non-randomized study, but not comparable to a rigorous randomized trial; Serious presence of important problems; Critical too problematic to provide any useful evidence on the effects of intervention; Overall risk of bias equal to the most severe level of bias found in any domain.