Table 3 Assessment of the certainty of evidence presented for each outcome.
Evaluation of certainty | Summary of outcomes | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
No. of studies | Study design | Risk of bias | Inconsistency | Indirect evidence | Imprecision | Other considerations | No. of patients | Effect | Certainty | ||
Therapeutic exercise | Control | Relative (95% CI) | Absolute (95% CI) | ||||||||
Aerobic exercise. Muscular strength – Sit-to-stand test (monitoring range 6–12 weeks; assessed with Number of repetitions) | |||||||||||
2 | not seriousa | not serious | not serious | seriousb | none | 26 | 29 | – | SMD 0.15 higher (− 0.48;1.27) | ⨁⨁⨁◯ Moderate | |
Combined exercise. Muscular strength—1 RM Leg press (monitoring range 10–12 weeks; assessed with Weight Lifted) | |||||||||||
2 | Seriousc | not serious | not serious | seriousb | none | 39 | 33 | – | SMD 0.56 higher (0.08;1.04) | ⨁⨁◯◯ Low | |
Combined exercise. Muscular strength—1 RM chest press (monitoring range 10–12 weeks; assessed with Weight lifted) | |||||||||||
2 | Seriousc | not serious | not serious | seriousb | none | 39 | 33 | – | SMD 0.73 higher (0.25;1.22) | ⨁⨁◯◯ Low | |
Balance | |||||||||||
4 | Seriousa | not serious | not serious | seriousb | none | 54 | 47 | Carmeli et al10 with aerobic exercise reported significant improvements in dynamic balance between groups p < 0.05. Cai et al.29 with a combined exercise plan showed significant increase of dynamic and static balance | ⨁⨁◯◯ Low | ||
Aerobic exercise. Gait | |||||||||||
1 | RCT13 | Seriousa | not serious | not serious | not serious | none | 11 | 11 | Skiba et al. found an improvement in the space–time parameters, angular changes of the limbs, and mean values of the angular deviations at the joints | ⨁⨁⨁◯ Moderate | |
Combined exercise. Functional Fitness—6 min walking distance (6MWD) (monitoring 14 weeks) | |||||||||||
1 | RCT28 | Seriousa | not serious | not serious | Not seriousa | none | 6 | 6 | Perrot et al. showed significant improvements in functional task using combined exercise via nintendo wii | ⨁⨁⨁◯ Moderate |